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DILAUDID (hydromorphone hydrochloride), a hydrogenated ketone of morphine, is an opioid agonist.
This medication is used to help relieve moderate to severe pain. Hydromorphone belongs to a class of drugs known as opioid (narcotic) analgesics. It works in the brain to change how your body feels and responds to pain. DILAUDID is used to relieve pain. Dilaudid (hydromorphone) is a schedule II-controlled substance prescribed for moderate to severe pain. The drug attaches to receptors in the brain and central nervous system to dull pain. Dilaudid also triggers the release of excessive amounts of dopamine in the brain, causing pleasurable feelings. This activates the reward center of the brain, which interprets the event as something that is important and should be repeated. The more this happens, the less the brain will naturally produce dopamine, and the more reliant the body becomes on Dilaudid. Hydromorphone extended-release tablets are used to relieve severe pain in people who are expected to need pain medication around the clock for a long time and who cannot be treated with other medications. DILAUDID extended-release tablets should only be used to treat people who are tolerant to opioid medications because they have taken this type of medication for at least one week and should not be used to treat mild or moderate pain, short-term pain, pain after an operation or medical or dental procedure, or pain that can be controlled by medication that is taken as needed. Hydromorphone is an opioid agonist that binds to several opioid receptors. Its analgesic characteristics are through its effect on the mu-opioid receptors. It also acts centrally at the level medulla, depressing the respiratory drive and suppressing cough. Hydromorphone is in a class of medications called opiate (narcotic) analgesics. It works by changing the way the brain and nervous system respond to pain. Currently approved hydromorphone products include tablets of 2, 4, and 8 mg, extended release tablets of 8, 12, 16, 32 mg, oral solution of 5 mg/5 ml viscous liquid, and ampules of 1, 2, 4, and 10 mg/ml sterile solution for parenteral administration. Pain medications work best if they are used when the first signs of pain occur. If you wait until the pain has worsened, the medication may not work as well. Dilaudid is one of the more powerful synthetic narcotics in the opioid class of drugs and an addiction to Dilaudid can rapidly develop through continued use. Hydromorphone, also known as dihydromorphinone, and sold under the brand name Dilaudid among others, is an opioid used to treat moderate to severe pain. Typically, long-term use is only recommended for cancer pain. It may be used by mouth or by injection into a vein, muscle, or under the skin. Effects generally begin within half an hour and last for up to five hours. Hydromorphone is a potent schedule II opioid analgesic drug. It is marketed as injectable ampules, multiple dose vials, tablets and suppositories. Hydromorphone is indicated for relief of moderate-to-severe pain. Hydromorphone is marketed under brand names, Dilaudid and Exalgo. It is also marketed in generic forms. DILAUDID Tablets are supplied in 2 mg, 4 mg, and 8 mg tablets for oral administration. The tablet strengths describe the amount of hydromorphone hydrochloride in each tablet. DILAUDID Oral Solution is supplied as 5mg/5 mL (1 mg/mL) viscous liquid. Dilaudid (hydromorphone) is an opioid pain medication. An opioid is sometimes called a narcotic. Dilaudid is used to treat moderate to severe pain. Dilaudid may also be used for purposes not listed here.
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INDICATIONS AND USAGE
Hydromorphone hydrochloride extended-release tablets are an opioid
agonist indicated in opioid-tolerant patients for the management of pain
severe enough to require daily, around-the-clock, long-term opioid
treatment and for which alternative treatment options are inadequate.
Patients considered opioid tolerant are those who are taking, for one
week or longer, at least 60 mg oral morphine per day, 25 mcg
transdermal fentanyl/hour, 30 mg oral oxycodone/day, 8 mg oral
hydromorphone/day, 25 mg oral oxymorphone/day or an equianalgesic
dose of another opioid.
DOSAGE AND ADMINISTRATION
Dilaudid exist as Dilaudid oral Solution and Dilaudid Tablets
tablet: immediate-release 2mg, 4mg, 8mg
tablet, extended-release: 8mg, 12mg, 16mg, 32mg
injection solution: 1mg/mL, 2mg/m, L4mg/mL
injection solution, preservative free: 10mg/mL
oral liquid: 5 mg/5 mL (1 mg/mL)
Use the lowest effective dosage for the shortest duration consistent with individual patient treatment goals.
Hydromorphone administration can be administered through intramuscular, intravenous, subcutaneous, or oral routes at a concentration up to 10 mg/ml.
Buy dilaudid online without prescription Usual adult dosage of Dilaudid Oral Solution is one-half (2.5 mL) to two teaspoonful (10 mL) (2.5 mg – 10 mg) every 3 to 6 hours. The usual adult starting dose for Dilaudid Tablets is 2 mg to 4 mg, orally, every 4 to 6 hours.
Hepatic Impairment: Initiate treatment with one-fourth to one-half the usual starting dose, depending on degree of hepatic impairment. Renal Impairment: Initiate treatment with one-fourth to one-half the usual starting dose, depending on degree of renal impairment.
Orals: Patients can take it orally with or without food in the immediate or extended-release form. It cannot be crushed, chewed, or dissolved, because it will void immediate release of the formulation. Immediate-release oral formulations have an onset of action at 15 to 30 minutes, peak at 30 to 60 minutes, and last 3 to 4 hours. Extended-release formulations have an onset of action at 6 hours, peak at 9 hours, and lasts 13 hours.
Recommended dosage usually starts out at 2-4 mg every 4-6 hours but can be adjusted based on the patient’s needs.
-For once daily administration.
-Instruct patients to swallow hydromorphone hydrochloride extended-release tablets intact.
-Do not abruptly discontinue hydromorphone hydrochloride extended-release tablets.
Dose may be increased using increments of 4 to 8 mg every 3 to 4 days as needed to achieve adequate analgesia.
Dilaudid Injection: The usual starting dose is 1 mg to 2 mg subcutaneously or intramuscularly every 2 to 3 hours as necessary.
Dilaudid-HP Injection should be used only if the amount of hydromorphone required can be delivered accurately with this formulation.
The dose should be adjusted according to the severity of pain, as well as the patient’s underlying disease state and age.
Should intravenous administration be necessary, the injection should be given slowly, over at least 2 to 3 minutes and the usual starting dose is 0.2 to 1 mg.
Dilaudid Side Effects
Drowsiness, tiredness, Agitation, decreased urination, blurred vision, rapid breathing, headache, constipation, changes in behavior, nausea, severe stomach pain, cramping, or burning, vomiting, stomach pain, bloating or swelling of the face, arms, hands, lower legs, or feet, Slowed breathing, fast, pounding, slow, or irregular heartbeat, Loss of appetite and Itching. Contact your doctor for more side effects.
Flushing (warmth, redness, or tingling of skin), itching, sweating, nausea, vomiting, constipation, diarrhea, stomach pain, dizziness, Seizures, Confusion, drowsiness, blurred vision, double vision, headache, sleep problems (insomnia), strange dreams, and dry mouth. Just like with any other drug, not everybody experiences these side effects. If any symptoms persist, contact your doctor. Buy Pain Pills Online
How to use Dilaudid
Buy dilaudid online without prescription Take this medication by mouth as directed by your doctor. You may take this drug with or without food. If you have nausea, it may help to take this drug with food. Ask your doctor or pharmacist about other ways to decrease nausea (such as lying down for 1 to 2 hours with as little head movement as possible).
If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose. Do not confuse the dose of hydromorphone liquid in milligrams (mg) with the dose in milliliters (mL). Ask your pharmacist or doctor if you are not sure how to check or measure the dose. If your liquid is a suspension, shake the bottle well before each dose.
The dosage is based on your medical condition and response to treatment. Do not increase your dose, take the medication more frequently, or take it for a longer time than prescribed. Properly stop the medication when so directed.
If you have ongoing pain (such as due to cancer), your doctor may direct you to also take long-acting opioid medications. In that case, this medication might be used for sudden (breakthrough) pain only as needed. Other pain relievers (such as acetaminophen, ibuprofen) may also be prescribed. Ask your doctor or pharmacist about using hydromorphone safely with other drugs.
Suddenly stopping this medication may cause withdrawal, especially if you have used it for a long time or in high doses. To prevent withdrawal, your doctor may lower your dose slowly. Tell your doctor or pharmacist right away if you have any withdrawal symptoms such as restlessness, mental/mood changes (including anxiety, trouble sleeping, thoughts of suicide), watering eyes, runny nose, nausea, diarrhea, sweating, muscle aches, or sudden changes in behavior.
Buy dilaudid online without prescription When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well.
Though it helps many people, this medication may sometimes cause addiction. This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Take this medication exactly as prescribed to lower the risk of addiction. Ask your doctor or pharmacist for more details.
Tell your doctor if your pain does not get better or if it gets worse.